The total number of records retrieved from this search are 1. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_46	Virus nameAdenovirus	Virus strainAd-cycE	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationE1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFemale FVB/NCr mice isograft for 5.0E+6 cells ED-1 murine lung cancer cell lines	In-vivo virus concentration1.5E+9 IFU (on 0, 2, 4 and 6 days)	In-vivo toxicityNA	In-vivo resultReduction in tumor volume to 52 cubic millimeter compared to control 150 cubic millimeter after 36 days	Mode of deliveryIntratumorally	Pathway inducedNA	Immunogenic effectActivates CDK2 and targets the transcriptional repressor pRb	Clinical trialNA	PMID26475304