The total number of records retrieved from this search are 2. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_854	Virus nameHerpes simplex virus	Virus strainHSV-G207	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutant in ICP34.5 and ICPC6 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFemale CB17 SCID mice model xenograft for SKOV3 cell	In-vivo virus concentration5.0E+6 pfu	In-vivo toxicityNA	In-vivo resultReduction in tumor growth to 50mg compared to control of 300mg within week	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID10770637
IDOV_2896	Virus nameVaccinia virus	Virus strainvvDD	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationDeletion of TK gene and vaccinia growth factor	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineLaboratory grown own culture	Origin of cell lineNeuroblastoma cell line SKNASmCherryFluc	Cell lineSK-N-ASmCherryFluc	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismCB17 SCID mice xenograft for cell line (5.0E+6)	In-vivo virus concentration5.0E+7 pfu	In-vivo toxicityNA	In-vivo resultSignificant reduction in tumor volume	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID23816608