Browse By Model Organism Result Page of OvirusTdb
The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_1263 | Virus nameAdenovirus | Virus strainAxdAdb-3 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationDouble mutated for E1A and E1B gene | Virus aloneNo | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCB-17/Icr-SCID mice orthotopic for DU145 cell line | In-vivo virus concentration1.0E+6 pfu per kg | In-vivo toxicityNA | In-vivo resultTumor weight goes down to 100mm after 4 weeks | Mode of deliveryIntratumorally | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18063085 |