Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_1263Virus nameAdenovirusVirus strainAxdAdb-3Virus genome typeDNAVirus familyAdenoviridaeVirus genome modificationDouble mutated for E1A and E1B geneVirus aloneNoVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismCB-17/Icr-SCID mice orthotopic for DU145 cell lineIn-vivo virus concentration1.0E+6 pfu per kgIn-vivo toxicityNA In-vivo resultTumor weight goes down to 100mm after 4 weeksMode of deliveryIntratumorallyPathway inducedNAImmunogenic effectNAClinical trialNAPMID18063085