The total number of records retrieved from this search are 1. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_4979	Virus nameVaccinia virus	Virus strainvv-IL-24	Virus genome typeDNA	Virus familyPoxviridae	Virus genome modificationInsertion of IL-24 gene in tk locus	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineNA	Cell lineNA	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismC54BL/6 mice xenograft for A549 cell line (5.0E+6)	In-vivo virus concentration1.0E+7 pfu	In-vivo toxicityNA	In-vivo resultReduction in tumor volume to 1000 cubic mm compared to control 2200 cubic mm after 27 days	Mode of deliveryIntratumoral	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID27208781