Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 2. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4287AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman glioblastoma multiformeT98G4000 cells per wellNAMTT assay10 pfu38.2 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5343Newcastle disease virusLaSotaRNAParamyxoviridaeNoneYesNoNoATCCHuman glioblastoma multiformeT98G5.0E+4 cells per wellNAMTT assay0.001 MOI29% cells remain viable after 72 hoursNoNoNA No responseNAVirus induce apoptosisInduced production of IFN-alpha, IFN-beta, IL-6and IFN-gammaNA28293547