The total number of records retrieved from this search are 15. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3747	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.0001 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3748	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.001 MOI	100% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3749	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3750	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	1 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3751	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	2 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3752	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	3 MOI	100% cell killing after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3763	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3764	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3765	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3766	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	30% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3771	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3772	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 500mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3773	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3774	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 300mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_4293	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human pancreas epithelioid carcinoma	SW1990	4000 cells per well	NA	MTT assay	10 pfu	45.6 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347