Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 8. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2731AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI100% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2732AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI90% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2733AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI60% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2734AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI50% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2735AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI90% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2736AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2737AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI50% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2738AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell linePLC51.0E+4 cells per wellNAMTT assay5 MOI30% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172