The total number of records retrieved from this search are 13. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2212	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	50% cell survival after day 1	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2213	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	55% cell survival after day 2	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2214	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	60% cell survival after day 3	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2215	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	30% cell survival after day 4	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2216	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	100% cell death after day 5	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2217	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	40% cell survival after day 1	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2218	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	20% cell survival after day 2	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2219	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	10% cell survival after day 3	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2220	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	100% cell death after day 4	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2221	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	100% cell death after day 5	No	No	NA	No response	NA	Caspase activation	NA	NA	22108767
OV_2252	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	State key laboratory of oncology China	Human breast cancer cell line	MDA-MB-435	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for MDA-MB-435(1.0E+6 × 10⁶)	2.0E+7 pfu	NA	Tumor volume decreased by 9 fold after 56 days	Intratumoral	Caspase activation	NA	NA	22108767
OV_4429	Vesicular stomatitis virus	RdB	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, no addition of linker	Yes	No	No	ATCC	Human breast cancer cell line	MDA-MB-435	1.2E+4 cells per well	NA	MTT assay	21:1 particle to pfu	98% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798
OV_4437	Vesicular stomatitis virus	RdB-1L-VSVG	RNA	Rhabdoviridae	Virus expressing VSVG epitope, with no dletion in HI-loop, addition of single linker	Yes	No	No	ATCC	Human breast cancer cell line	MDA-MB-435	1.2E+4 cells per well	NA	MTT assay	24:1 particle to pfu	2% cell survival after 4 days	No	No	NA	No response	NA	NA	NA	NA	26430798