Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 10. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5422Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI64% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5423Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI40% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5424Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI17% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5425Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI70% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5426Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI60% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5427Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI35% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5553ReovirusReovirus serotype 3RNAReoviridaeNoneYesNoNoATCCHuman breast cancer cell lineSKBR360% confluencyNANA40 MOICell viability drops from 93 to 16% after 72 hoursNoNoNA No responseNAInduction of apoptosis by virus infectionNANAUS6994858
OV_5626Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman head and neck carcinoma cell lineKB80% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5824Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman breast carcinoma cell lineSKBR380% confluencyNANA10 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578
OV_5846Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman head and neck carcinoma cell lineKB80% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578