Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5270Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5271Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay0.33 PFU70% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5272Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay1 PFU58% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5273Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay3.3 PFU30% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5274Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay10 PFU15% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5275Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay33 PFU1% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5276Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineIg104000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340