Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 36. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_276	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_277	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	90% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_278	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	85% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_279	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	83% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_280	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	92% cancer cell viability at 24 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_281	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	94% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_282	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	86% cancer cell viability at 96 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_291	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	91% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_292	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	85% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_293	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	65% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_294	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	56% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_295	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	92% cancer cell viability at 24 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_296	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	81% cancer cell viability at 48 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_297	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	61% cancer cell viability at 96 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_301	Adenovirus	Ad.sp-E1A	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP)	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	100% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_302	Adenovirus	Ad.IL3	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-IL3 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	90% cancer cell viability at 48 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_303	Adenovirus	Ad.4N1	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	80% cancer cell viability at 48 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_304	Adenovirus	Ad.IL3	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-IL3 expression cassette	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	100% cancer cell viability at 72 hours	No	No	NA	No response	NA	NA	NA	NA	26554307
OV_310	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	50 MOI	82% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_311	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	100 MOI	58% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_312	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	150 MOI	52% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_313	Adenovirus	Ad.4N1-IL24	DNA	Adenoviridae	Viral E1A promoter was replaced by human survivin promoter (hsurP) and contains a sCAR-4N1 with IL-24 expression cassettes	Yes	No	No	ATCC	Leukemia cell line	HL-60	2.0E+4 cells per well	NA	MTT assay	200 MOI	38% cancer cell viability at 72 hours	No	No	NA	No response	NA	Induces apoptosis by upregulating Bax and activated caspase 3 levels	Induces expression of IL-24	NA	26554307
OV_768	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_769	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	60% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_770	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	50% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_771	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	46% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_772	Adenovirus	SG611	DNA	Adenoviridae	None	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	40% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_798	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	10 MOI	80% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_799	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	40 MOI	40% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_800	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	80 MOI	32% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_801	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	120 MOI	25% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_802	Adenovirus	SG611-VSTM1	DNA	Adenoviridae	A VSTM1 gene expression cassette containing VSTM1 cDNA, cytomegalovirus promoter and SV40 polyA was inserted into the genome of SG611 to generate SG611-VSTM1	Yes	No	No	Gibco, Thermo Fisher Scientific, Waltham, MA, USA	Human acute promyelocytic leukemic cell line	HL-60	1.0E+4 cells per well	Slight toxicity to L-02 and BJ cell line	Cell counting kit-8 (CCK-8) assay	160 MOI	20% cancer cell viability at 72 hours	No	No	NA	No response	NA	Enhanced apoptosis activation is observed	NA	NA	27472927
OV_2903	Measles virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	Laboratory grown own culture	Leukemia cell line	HL-60	5000 cells per well	NA	Luminiscent cell viability assay	1 MOI	100% cell viability	No	No	NA	No response	NA	Induction of apoptosis by virus alone and in combination	NA	NA	25193462
OV_2904	Mumps virus	wild type	RNA	Paramyxoviridae	None	Yes	No	No	Laboratory grown own culture	Leukemia cell line	HL-60	5000 cells per well	NA	Luminiscent cell viability assay	1 MOI	75% cell viability	No	No	NA	No response	NA	Induction of apoptosis by virus alone and in combination	NA	NA	25193462
OV_2905	Measles and mumps virus	wild type	RNA	Paramyxoviridae	None	No	Measles in combination with mumps	No	Laboratory grown own culture	Leukemia cell line	HL-60	5000 cells per well	NA	Luminiscent cell viability assay	1 MOI	40% cell viabiity	No	No	NA	No response	NA	Induction of apoptosis by virus alone and in combination	NA	NA	25193462
OV_4316	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	ATCC	Human acute promyelocytic leukemia	HL-60	4000 cells per well	NA	MTT assay	10 pfu	85.2 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347