Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1448	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	EKVX	NA	NA	XTT assay	Log10 pfu/cell	30% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1456	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.294 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1462	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.440	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1468	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.660	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1474	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.124 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1480	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.216	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1486	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.374	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1492	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.955	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1498	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.559	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1504	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.328	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1510	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.933	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1516	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1522	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.610	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1528	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1534	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1540	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1546	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1552	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1558	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI >10	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1564	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 3.275	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1570	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 1.927	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1576	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:20)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 1.134	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1582	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.193	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1588	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.651	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1594	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(>100, 1:200)	No	NCI	Human NSCLC cell line	EKVX	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 2.192	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950