Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2862AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay0.1 MOI100% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2863AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay1 MOI40% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2864AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay10 MOI20% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2865AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB21.0E+5 cells per wellNAMTT assay100 MOI10% cell survivalNoNoNA No responseNAIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23586034
OV_2866AdenovirusSG7605-11R-p53DNAAdenoviridaeAddition of p53 gene and 11R CPPYesNoNoEastern hepatobility hospitalGallbladder cancer cell lineEH-GB2NANANANANABALB/c nude mice xenograft for EH-GB21.0E+9 pfuNA Signficant reduction in tumor volume after day 30 and increase in median survival timeIntratumoralIncrease in apoptosis rate to 67% in cancer cell compared to normalNANA23727990