The total number of records retrieved from this search are 3. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_43	Adenovirus	AdCMV/GFP	DNA	Adenoviridae	Mutant with E1 deletion carrying a green fluorescent protein (GFP)	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Highly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	22% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_44	Adenovirus	Ad dl1520	DNA	Adenoviridae	E1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	NA	NA	26475304
OV_45	Adenovirus	Ad-cycE	DNA	Adenoviridae	E1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Yes	No	No	ATCC	Murine lung cancer cell line	ED-1	Desnity of 1000000 in 60mm dish	Minimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	MTT assay	10 MOI	55% cancer cell viability	No	No	NA	No response	NA	NA	Activates CDK2 and targets the transcriptional repressor pRb	NA	26475304