Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 38. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1330AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.01 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1331AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.1 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1332AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining1 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1333AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining10 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1334AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1335AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.01 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1336AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.1 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1337AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining1 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1338AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining10 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1339AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1340AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.01 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1341AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining0.1 MOISome cell are viableNoNoNA No responseNANANANA18281783
OV_1342AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining1 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1343AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining10 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1344AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100 MOI100% cell killingNoNoNA No responseNANANANA18281783
OV_1345AdenovirusAdCN101DNAAdenoviridae24bp deletion between E1Ap and E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100MOI50% cell killing after 96 hoursNoNoNA No responseNANANANA18281783
OV_1346AdenovirusAdCN102DNAAdenoviridaeAddition of hTERT promoter ahead of E1AYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100MOI50% cell killing after 96 hoursNoNoNA No responseNANANANA18281783
OV_1347AdenovirusAdCN103DNAAdenoviridae24 bp deletion in hTERT promoterYesNoNoShanghai institute for biological scincesHuman hepatocellular carcinoma cell lineBEL-7404NANACrystal violet staining100MOI30% cell killing after 96 hoursNoNoNA No responseNANANANA18281783
OV_2081AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANACrystal violet staining0.1 MOINo cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2082AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANACrystal violet staining1 MOISome cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2083AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANACrystal violet staining10 MOISome cell death observedNoNoNA No responseNAInduction of senescenceNANA21794078
OV_2084AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANACrystal violet staining100 MOIAll cells was deadNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2085AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANAMTT assay1 MOIAbsorbance decrease to below 0.2 after 24 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2086AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANAMTT assay1 MOIAbsorbance decrease to below 0.2 after 48 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2087AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANAMTT assay1 MOIAbsorbance decrease to below 0.2 after 72 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2088AdenovirusMutantDNAAdenoviridaeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassetteYesNoVirus expressing IL-24 geneNAHuman cellosaurus cell lineBEL-7404NANAMTT assay1 MOIAbsorbance decrease to below 0.2 after 96 hoursNoNoNA No responseNAInduction of apoptosisNANA21794078
OV_2690AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneShanghai cell collectionHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNASpectrophotometer10 MOI85% cell viability after 24 hoursNoNoNA No responseNANANANA23028626
OV_2691AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneShanghai cell collectionHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNASpectrophotometer10 MOI80% cell viability after 48 hoursNoNoNA No responseNANANANA23028626
OV_2692AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneShanghai cell collectionHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNASpectrophotometer10 MOI60% cell viability after 72 hoursNoNoNA No responseNANANANA23028626
OV_2693AdenovirusAdCN205-IL12DNAAdenoviridaeNoneYesNoVirus expressing IL-12 geneShanghai cell collectionHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNASpectrophotometer10 MOI50% cell viability after 96 hoursNoNoNA No responseNANANANA23028626
OV_2739AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI100% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2740AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI90% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2741AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI82% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2742AdenovirusAdCN205DNAAdenoviridaeNoneYesNoVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI78% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2743AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI90% cell viability after 24 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2744AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI80% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2745AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI60% cell viability after 72 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172
OV_2746AdenovirusAdCN205DNAAdenoviridaeNoneNoVirus strain in combination with miR-34-aVirus expressing IL-24 geneATCCHuman hepatocellular carcinoma cell lineBEL-74041.0E+4 cells per wellNAMTT assay5 MOI40% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosis, G1 arrest and sensescenceInhibition of oncogene and antiapototic geneNA23292172