The total number of records retrieved from this search are 54. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_489	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	Yes	No	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	1 MOI	98% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_493	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	Yes	No	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	5 MOI	85% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_497	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	Yes	No	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	10 MOI	96% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_501	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	Yes	No	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	50 MOI	78% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_505	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	Yes	No	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	100 MOI	60% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_509	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 0.4 μg/ml ) and doxorubicin (DOX, 0.1 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	1 MOI	90% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_513	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 0.4 μg/ml ) and doxorubicin (DOX, 0.1 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	5 MOI	88% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_517	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 0.4 μg/ml ) and doxorubicin (DOX, 0.1 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	10 MOI	70% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_521	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 0.4 μg/ml ) and doxorubicin (DOX, 0.1 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	50 MOI	50% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_525	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 0.4 μg/ml ) and doxorubicin (DOX, 0.1 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	100 MOI	32% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_529	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 2.0 μg/ml ) and doxorubicin (DOX, 0.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	1 MOI	66% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_533	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 2.0 μg/ml ) and doxorubicin (DOX, 0.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	5 MOI	58% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_537	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 2.0 μg/ml ) and doxorubicin (DOX, 0.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	10 MOI	50% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_541	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 2.0 μg/ml ) and doxorubicin (DOX, 0.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	50 MOI	38% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_545	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 2.0 μg/ml ) and doxorubicin (DOX, 0.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	100 MOI	23% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_549	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 10.0 μg/ml ) and doxorubicin (DOX, 2.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	1 MOI	16% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_553	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 10.0 μg/ml ) and doxorubicin (DOX, 2.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	5 MOI	16% cancer cell viability (calculated as relative to mock-infected group)	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_557	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 10.0 μg/ml ) and doxorubicin (DOX, 2.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	10 MOI	16% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_561	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 10.0 μg/ml ) and doxorubicin (DOX, 2.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	50 MOI	16% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_565	Adenovirus	OBP-301 (telomelysin)	DNA	Adenoviridae	Viral mutant with human telomerase reverse transcriptase (hTERT) promotor for selective replication in cancer cells	No	Viral strain in combination with cisplatin (CDDP, 10.0 μg/ml ) and doxorubicin (DOX, 2.5 μg/ml )	No	ATCC	Human osteosarcoma cell line	143-B	1.0E+3 cells per well	NA	XTT assay	100 MOI	12% cancer cell viability (calculated as relative to mock-infected group), synergistic effect with drugs	No	No	NA	No response	NA	NA	NA	NA	27356624
OV_2867	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Osteosarcoma cell line	143-B	5.0E+3 cells per well	NA	MTT assay	0.01 MOI	80% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2868	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Osteosarcoma cell line	143-B	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	70% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2869	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Osteosarcoma cell line	143-B	5.0E+3 cells per well	NA	MTT assay	1 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_2870	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	Laboratory grown own culture	Osteosarcoma cell line	143-B	5.0E+3 cells per well	NA	MTT assay	10 MOI	40% cell survival	No	No	NA	No response	NA	NA	NA	NA	23816608
OV_3207	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3208	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3209	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3210	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3211	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3212	Herpes simplex virus	wild type	DNA	Herpesviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3213	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3214	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3215	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	80% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3216	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3217	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3218	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3219	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3220	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	73% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3221	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	60% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3222	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	55% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3223	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	50% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3224	Vaccinia virus	wild type	DNA	Poxviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	40% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3225	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	70% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3226	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3227	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	25% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3228	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3229	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3230	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3231	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.0001 MOI	75% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3232	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.001 MOI	50% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3233	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.01 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3234	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	0.1 MOI	20% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3235	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	1 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891
OV_3236	Maraba virus	MG1	RNA	Rhabdoviridae	None	Yes	No	No	ATCC	Human bone osteosarcoma cell line	143-B	90% confluence	NA	Crystal violet staining and absorbance at 595 nm	10 MOI	10% cell survival after 48 hours	No	No	NA	No response	NA	NA	Genration of memory immune response by incresing production of cytokines	NA	28568891