Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 2. Click on ID to see further detail.
IDOV_4287Virus nameAlphavirusVirus strainM1Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman glioblastoma multiformeCell lineT98GConcentration of cell line4000 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration10 pfuIn-vitro result38.2 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisImmunogenic effectNAClinical trialNAPMID26373347
IDOV_5343Virus nameNewcastle disease virusVirus strainLaSotaVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman glioblastoma multiformeCell lineT98GConcentration of cell line5.0E+4 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration0.001 MOIIn-vitro result29% cells remain viable after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosisImmunogenic effectInduced production of IFN-alpha, IFN-beta, IL-6and IFN-gammaClinical trialNAPMID28293547