Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 36. Click on ID to see further detail.
IDOV_1149 | Virus nameHerpes simplex virus | Virus strainNV1020 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon carcinoma cell line | Cell lineSW480 | Concentration of cell line2.0E+4 cells per well | In-vitro toxicityNA | AssayWST-1 assay | In-vitro virus concentration1 × 10ⶠpfu/ml | In-vitro result70% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID17117895 |
IDOV_2154 | Virus nameEnterovirus | Virus strainEnterovirus B species echovirus 12 | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMicroscopy examination | In-vitro virus concentration1 MOI | In-vitro resultComplete cell death after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus can cause induction in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21999585 |
IDOV_2155 | Virus nameEnterovirus | Virus strainEnterovirus B species echovirus 15 | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMicroscopy examination | In-vitro virus concentration1 MOI | In-vitro resultPartial cell death after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus can cause induction in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21999585 |
IDOV_2156 | Virus nameEnterovirus | Virus strainEnterovirus B species echovirus 17 | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMicroscopy examination | In-vitro virus concentration1 MOI | In-vitro resultComplete cell death after 6 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus can cause induction in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21999585 |
IDOV_2157 | Virus nameEnterovirus | Virus strainEnterovirus B species echovirus 26 | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMicroscopy examination | In-vitro virus concentration1 MOI | In-vitro resultPartial cell death after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus can cause induction in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21999585 |
IDOV_2158 | Virus nameEnterovirus | Virus strainEnterovirus B species echovirus 29 | Virus genome typeRNA | Virus familyPicornaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineColon cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMicroscopy examination | In-vitro virus concentration1 MOI | In-vitro resultComplete cell death after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus can cause induction in apoptosis | Immunogenic effectNA | Clinical trialNA | PMID21999585 |
IDOV_2850 | Virus nameMeasles virus | Virus strainAttenuated strain | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineLaboratory grown own culture | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line1 million cells per well | In-vitro toxicityNA | AssayCell death detection kit | In-vitro virus concentration1 MOI | In-vitro result40% cells survived | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of caspase-3 | Immunogenic effectNA | Clinical trialNA | PMID23586034 |
IDOV_3570 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result98% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3571 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3572 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3573 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result70% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3574 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result98% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3575 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3576 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3577 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result55% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3578 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result95% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3579 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3580 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3581 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result40% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3582 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3583 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3584 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result20% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3585 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result20% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3586 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3587 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3588 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result10% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3589 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result10% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3590 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result60% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3591 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3592 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result10% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_3593 | Virus nameAdenovirus | Virus strainAdenovirus CD55-TRAIL | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationVirus expressingTRAIL gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with luteolin (25 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineShanghai cell collection | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration15 MOI | In-vitro result8% cell viability after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus in combination with induce apiptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID29039580 |
IDOV_4300 | Virus nameAlphavirus | Virus strainM1 | Virus genome typeRNA | Virus familyTogaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman colorectal adenocarcinoma | Cell lineSW480 | Concentration of cell line4000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 pfu | In-vitro result53.8 % cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis | Immunogenic effectNA | Clinical trialNA | PMID26373347 |
IDOV_5156 | Virus nameAdenovirus | Virus strainAd-ZD55-miR143 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion of miR143 in adenovirus via homologus recombination | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineChinese academy of science | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID27725862 |
IDOV_5157 | Virus nameAdenovirus | Virus strainAd-ZD55-miR143 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion of miR143 in adenovirus via homologus recombination | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineChinese academy of science | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID27725862 |
IDOV_5158 | Virus nameAdenovirus | Virus strainAd-ZD55-miR143 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion of miR143 in adenovirus via homologus recombination | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineChinese academy of science | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration1 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID27725862 |
IDOV_5159 | Virus nameAdenovirus | Virus strainAd-ZD55-miR143 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationInsertion of miR143 in adenovirus via homologus recombination | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineChinese academy of science | Origin of cell lineHuman colorectal cancer cell line | Cell lineSW480 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration10 MOI | In-vitro result100% cell killing | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID27725862 |