| Primary information |
|---|
| OV_ID | OV_5156 |
| Virus Name | Adenovirus |
| Strain | Ad-ZD55-miR143 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Insertion of miR143 in adenovirus via homologus recombination |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | Chinese academy of science |
| Origin of cell line | Human colorectal cancer cell line |
| Cell line | SW480 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | Crystal violet staining |
| In-vitro virus concentration | 0.01 MOI |
| In-vitro result | 100% cell viability |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Virus induced apoptosis as measured by TUNEL assay |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 27725862 |