Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 4. Click on ID to see further detail.
IDOV_4209Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineDr. T. Sugimoto, JapanOrigin of cell lineHuman neuroblastoma cell lineCell lineRT-BM-1Concentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration1 MOIIn-vitro result8 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4222Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineDr. T. Sugimoto, JapanOrigin of cell lineHuman neuroblastoma cell lineCell lineRT-BM-1Concentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration0.01 MOIIn-vitro result20 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4223Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineDr. T. Sugimoto, JapanOrigin of cell lineHuman neuroblastoma cell lineCell lineRT-BM-1Concentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration0.1 MOIIn-vitro result10 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056
IDOV_4224Virus nameSindbis virusVirus strainAR339Virus genome typeRNAVirus familyTogaviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineDr. T. Sugimoto, JapanOrigin of cell lineHuman neuroblastoma cell lineCell lineRT-BM-1Concentration of cell line1.0E+5 cells per wellIn-vitro toxicityNAAssayLuminiscence measurementIn-vitro virus concentration1 MOIIn-vitro result5 % cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedVirus induce apoptosis process leads to cancer cell deathImmunogenic effectIncreased expression of Bcl-2 and Bcl-xL expressionClinical trialNAPMID26298056