Detailed description page of Selected OV_ID


OV_4209 details
Primary information
OV_IDOV_4209
Virus Name Sindbis virus
StrainAR339
Virus typeRNA
Virus familyTogaviridae
Modification in virus genomeNone
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineDr. T. Sugimoto, Japan
Origin of cell lineHuman neuroblastoma cell line
Cell lineRT-BM-1
Concentration of cell line1
In-vitro toxicityNA
AssayLuminiscence measurement
In-vitro virus concentration1 MOI
In-vitro result8 % cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce apoptosis process leads to cancer cell death
Immunogenic effectIncreased expression of Bcl-2 and Bcl-xL expression
Clinical trialNA
PMID26298056