The total number of records retrieved from this search are 8. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3063	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	80% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3064	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	50% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3065	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	10% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3093	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻⁴ MOI	85% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3094	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻³ MOI	45% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3095	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	Yes	No	No	ECACC	Human eosophageal cancer cell line	OE19	3.0E+5 cells per well	NA	Trypan blue assay	10⁻² MOI	5% cell viability	No	No	NA	No response	NA	NA	NA	NA	31011628
OV_3107	Vaccinia virus	DeltaJ2R/FCU1 VACV	DNA	Poxviridae	Deletion of J2R gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ECACC	Human colon cancer cell line	OE19	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to below 1000 mm after 50 days	Intravenous	NA	NA	NA	31011628
OV_3108	Vaccinia virus	DeltaJ2R-I4L/FCU1 VACV (TG6002)	DNA	Poxviridae	Deletion of J2R and I4L gene and insertion of gene FCU1	No	Virus strain in combination with 5-FC (200mg/kg)	No	ECACC	Human colon cancer cell line	OE19	NA	NA	NA	NA	NA	BD62 mice xenograft for Lovo cell line	1.0E+7 pfu	NA	Tumor volume decreases to 250 mm after 50 days	Intravenous	NA	NA	NA	31011628