Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1449	Reovirus	ReoT3D	RNA	Reoviridae	None	Yes	No	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	XTT assay	Log10 pfu/cell	20% cell survived 48 hours after post infection	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1455	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.577 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1461	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.303	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1467	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.159	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1473	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death occurs at 0.329 CI value	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1479	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell death at CI value 0.061	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1485	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with palcitaxel (0.08 +/- 0.04 micromolar, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.011	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1491	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.579	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1497	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.487	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1503	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.530	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1509	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.546	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1515	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% death at CI value 0.207	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1521	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with cisplatin (3.51+/- 1.15, ratio is 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell death at CI value 0.342	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1527	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell death at CI value 0.630	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1533	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75 % cell death at CI 0.249	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1539	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.285	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1545	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.207	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1551	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.092	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1557	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus in combination with Gemcitabine (0.02+/- 0.01, 1:200)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.369	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1563	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.316	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1569	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.056	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1575	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:2)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.019	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1581	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	50% cell killing at CI 0.367	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1587	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	75% cell killing at CI 0.052	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950
OV_1593	Reovirus	ReoT3D	RNA	Reoviridae	None	No	Virus combination with vinblastine(1.49+/-1.09nm, 1:20)	No	NCI	Human NSCLC cell line	NCI-H23	NA	NA	chou-Talay analysis	Log10 pfu/cell	90% cell killing at CI 0.008	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19594950