Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4454Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4754000 to 5000 cells per wellNAMTS assay0.04 MOI45% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4458Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4754000 to 5000 cells per wellNAMTS assay0.11 MOI35% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4462Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4754000 to 5000 cells per wellNAMTS assay0.33 MOI20% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4466Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4754000 to 5000 cells per wellNAMTS assay1 MOI15% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4470Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN4754000 to 5000 cells per wellNAMTS assay3 MOI12% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380