Detailed description page of Selected OV_ID


OV_4458 details
Primary information
OV_IDOV_4458
Virus Name Herpes simplex virus
StrainG47-delta-mCherry
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineHuman patient
Origin of cell linemalignant leningioma
Cell lineMN475
Concentration of cell line4000
In-vitro toxicityNA
AssayMTS assay
In-vitro virus concentration0.11 MOI
In-vitro result35% cell viablity after 96 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID26951380