Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 5. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4455Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN2984000 to 5000 cells per wellNAMTS assay0.04 MOI70% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4459Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN2984000 to 5000 cells per wellNAMTS assay0.11 MOI55% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4463Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN2984000 to 5000 cells per wellNAMTS assay0.33 MOI50% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4467Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN2984000 to 5000 cells per wellNAMTS assay1 MOI30% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380
OV_4471Herpes simplex virusG47-delta-mCherryDNAHerpesviridaeDeletion mutant for Gamma 34.5, alpha47 and LacZ insertion inactivating ICP6YesNoNoHuman patientmalignant leningiomaMN2984000 to 5000 cells per wellNAMTS assay3 MOI25% cell viablity after 96 hoursNoNoNA No responseNANANANA26951380