Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3119Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit0.25 MOI18% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3120Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit1 MOI40% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3121Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit2.5 MOI60% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3122Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit5 MOI75% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3123Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit10 MOI85% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3134Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationNoVirus in combination with PAI-1 (25 microgram/ml)NoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit10 MOI90% cell are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3137Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5MNANANANANABALB/c nude mice xenograft for KHM-5M cell line (2.5E+5)1.0E+6 CIU per doseNA Reduction in tumor weight and increase in survival time 41.6 +/- 15 daysIntratumoralCaspase dependent induction of apoptosis in vivo and in vitroNANA30969451