Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 10. Click on ID to see further detail.
IDOV_5422Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-3-1Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result64% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5423Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-3-1Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result40% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5424Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-3-1Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result17% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5425Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result70% cell viability after 24 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5426Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result60% cell viability after 48 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5427Virus nameVaccinia virusVirus strainLIVP-GFPVirus genome typeDNAVirus familyPoxviridaeVirus genome modificationDeletion mutant for tk geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineRussian academy of scienceOrigin of cell lineHuman cervical carcinomaCell lineKB-8-5Concentration of cell line9.0E+3 cells per wellIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration1 MOIIn-vitro result35% cell viability after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedReduction production of IL-6 indicating tumor inhibitionImmunogenic effectNAClinical trialNAPMID27538520
IDOV_5553Virus nameReovirusVirus strainReovirus serotype 3Virus genome typeRNAVirus familyReoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineATCCOrigin of cell lineHuman breast cancer cell lineCell lineSKBR3Concentration of cell line60% confluencyIn-vitro toxicityNAAssayNAIn-vitro virus concentration40 MOIIn-vitro resultCell viability drops from 93 to 16% after 72 hoursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis by virus infectionImmunogenic effectNAClinical trialNAPMIDUS6994858
IDOV_5626Virus nameNewcastle disease virusVirus strainNDV-MK107Virus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman head and neck carcinoma cell lineCell lineKBConcentration of cell line80% confluencyIn-vitro toxicityNAAssayMTT assayIn-vitro virus concentration4 pfuIn-vitro result50% of cancer cell death occursModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedInduction of apoptosis by virus infectionImmunogenic effectInduction of IFN-Gamma productionClinical trialNAPMIDUS7470426
IDOV_5824Virus nameNewcastle disease virusVirus strainNDV-PPMK107Virus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman breast carcinoma cell lineCell lineSKBR3Concentration of cell line80% confluencyIn-vitro toxicityNAAssayNAIn-vitro virus concentration10 pfuIn-vitro result50% cancer cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS8105578
IDOV_5846Virus nameNewcastle disease virusVirus strainNDV-PPMK107Virus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationNoneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineHuman head and neck carcinoma cell lineCell lineKBConcentration of cell line80% confluencyIn-vitro toxicityNAAssayNAIn-vitro virus concentration4 pfuIn-vitro result50% cancer cell deathModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS8105578