The total number of records retrieved from this search are 7. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4987	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	90% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4988	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0006 mg/ml + cisplatin 0.0019	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	60% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4989	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	No	Virus in combination with drugs pemetrexed 0.0006 mg/ml + carboplatin 0.083	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4998	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	1 VP per cell	100% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_4999	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	10 VP per cell	80% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_5000	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	100 VP per cell	40% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512
OV_5001	Adenovirus	ONCOS-102	DNA	Adenoviridae	Virus having 24 bp deletion in Rb binding site of E1A region and consisting of chmeric capsid protein and Human GM-CSF	Yes	No	Virus expressing human GM-CSF gene	DSMZ Germany	Human epitheliod mesothelioma	JL-1	1.0E+4 cells per well	NA	MTS assay	1000 VP per cell	20% cell viability after 3 days	No	No	NA	No response	NA	Virus induce apoptosis	NA	NA	27287512