Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 7. Click on ID to see further detail.
IDOV_5270Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.1 PFUIn-vitro result100% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5271Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration0.33 PFUIn-vitro result70% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5272Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration1 PFUIn-vitro result58% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5273Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration3.3 PFUIn-vitro result30% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5274Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration10 PFUIn-vitro result15% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5275Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration33 PFUIn-vitro result1% cell viableModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340
IDOV_5276Virus nameHerpes simplex virusVirus strainM002Virus genome typeDNAVirus familyHerpesviridaeVirus genome modificationDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeVirus expressing murine IL-12Source of cell lineNAOrigin of cell lineMurine ovarian adenocarcinoma cell lineCell lineIg10Concentration of cell line4000 cells per wellIn-vitro toxicityNAAssayAlamar blue assayIn-vitro virus concentration100 PFUIn-vitro result100% cell killingModel organismNoIn-vivo virus concentrationNoIn-vivo toxicityNA In-vivo resultNo responseMode of deliveryNAPathway inducedNAImmunogenic effectTumor specific T cell response inducedClinical trialNAPMID27784340