Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 8. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5064Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCMurine ovarian cell lineID81.0E+3 cells per wellNACrystal violet staining10 MOI100% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5263Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay0.1 PFU100% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5264Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay0.33 PFU70% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5265Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay1 PFU50% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5266Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay3.3 PFU30% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5267Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay10 PFU10% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5268Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay33 PFU1% cell viableNoNoNA No responseNANATumor specific T cell response inducedNA27784340
OV_5269Herpes simplex virusM002DNAHerpesviridaeDeletion mutant for both copies of gamma 34.5 gene and expressing murine IL-12 geneYesNoVirus expressing murine IL-12NAMurine ovarian adenocarcinoma cell lineID84000 cells per wellNAAlamar blue assay100 PFU100% cell killingNoNoNA No responseNANATumor specific T cell response inducedNA27784340