The total number of records retrieved from this search are 25. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_1448	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	AssayXTT assay	In-vitro virus concentrationLog10 pfu/cell	In-vitro result30% cell survived 48 hours after post infection	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1456	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell death occurs at 0.294 CI value	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1462	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% cell death at CI value 0.440	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1468	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell death at CI value 0.660	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1474	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell death occurs at 0.124 CI value	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1480	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% cell death at CI value 0.216	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1486	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with palcitaxel (56.06 +/- 15.87 micromolar, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell death at CI value 0.374	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1492	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell death at CI value 0.955	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1498	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% death at CI value 0.559	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1504	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell death at CI value 0.328	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1510	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell death at CI value 0.933	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1516	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% death at CI value >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1522	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with cisplatin (29.34+/- 6.62, ratio is 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell death at CI value 0.610	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1528	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell death at CI value >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1534	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75 % cell death at CI >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1540	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell killing at CI >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1546	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell killing at CI >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1552	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% cell killing at CI >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1558	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus in combination with Gemcitabine (>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell killing at CI >10	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1564	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell killing at CI 3.275	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1570	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% cell killing at CI 1.927	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1576	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:20)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell killing at CI 1.134	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1582	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result50% cell killing at CI 0.193	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1588	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result75% cell killing at CI 0.651	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950
IDOV_1594	Virus nameReovirus	Virus strainReoT3D	Virus genome typeRNA	Virus familyReoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus combination with vinblastine(>100, 1:200)	Immune gene insertion in viral genomeNo	Source of cell lineNCI	Origin of cell lineHuman NSCLC cell line	Cell lineEKVX	Concentration of cell lineNA	In-vitro toxicityNA	Assaychou-Talay analysis	In-vitro virus concentrationLog10 pfu/cell	In-vitro result90% cell killing at CI 2.192	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, activation of caspase 3	Immunogenic effectNA	Clinical trialNA	PMID19594950