The total number of records retrieved from this search are 3. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_43	Virus nameAdenovirus	Virus strainAdCMV/GFP	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationMutant with E1 deletion carrying a green fluorescent protein (GFP)	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineMurine lung cancer cell line	Cell lineED-1	Concentration of cell lineDesnity of 1000000 in 60mm dish	In-vitro toxicityHighly toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result22% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26475304
IDOV_44	Virus nameAdenovirus	Virus strainAd dl1520	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationE1b mutant with 827-bp deletion and a point mutation with premature stop codon in the E1B55K coding region	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineMurine lung cancer cell line	Cell lineED-1	Concentration of cell lineDesnity of 1000000 in 60mm dish	In-vitro toxicityMinimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result55% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID26475304
IDOV_45	Virus nameAdenovirus	Virus strainAd-cycE	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationE1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineMurine lung cancer cell line	Cell lineED-1	Concentration of cell lineDesnity of 1000000 in 60mm dish	In-vitro toxicityMinimal toxic to NIH/3T3 as measured by crystal violet staining at 10 MOI	AssayMTT assay	In-vitro virus concentration10 MOI	In-vitro result55% cancer cell viability	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectActivates CDK2 and targets the transcriptional repressor pRb	Clinical trialNA	PMID26475304