The total number of records retrieved from this search are 12. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_2169	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	98% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2170	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	90% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2171	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	70% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2172	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	30% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2173	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.01 MOI	10% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2174	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	85% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2175	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	70% cell survival after day 2	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2176	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	30% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2177	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	10% cell survival after day 4	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2178	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	1.0E+5 cells per well	NA	X-gal staining and MTT assay	0.1 MOI	All cells was dead after day 5	No	No	NA	No response	NA	NA	NA	NA	22059912
OV_2209	Herpes simplex virus	HSV-1-G47-delta	DNA	Herpesviridae	Mutant for Gamma34.5, ICP6 and alpha47 gene	Yes	No	No	Hongkong university	Human nasopharyngeal carcinoma cell line	CNE-2	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for CNE-2 cell line (1.0E+6 × 10⁶ cells)	2.0E+7 pfu	NA	Virus treated mice shows complete regression in tumor and exhibit longer survival time	Intratumoral	NA	NA	NA	22059912
OV_4281	Alphavirus	M1	RNA	Togaviridae	None	Yes	No	No	SICB	Human nasopharyngeal carcinoma	CNE-2	4000 cells per well	NA	MTT assay	10 pfu	24.5 % cell viability after 72 hours	No	No	NA	No response	NA	Activation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosis	NA	NA	26373347