The total number of records retrieved from this search are 38. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_1330	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.01 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1331	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.1 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1332	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration1 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1333	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration10 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1334	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1335	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.01 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1336	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.1 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1337	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration1 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1338	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration10 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1339	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1340	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.01 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1341	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.1 MOI	In-vitro resultSome cell are viable	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1342	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration1 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1343	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration10 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1344	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100 MOI	In-vitro result100% cell killing	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1345	Virus nameAdenovirus	Virus strainAdCN101	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24bp deletion between E1Ap and E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100MOI	In-vitro result50% cell killing after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1346	Virus nameAdenovirus	Virus strainAdCN102	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationAddition of hTERT promoter ahead of E1A	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100MOI	In-vitro result50% cell killing after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_1347	Virus nameAdenovirus	Virus strainAdCN103	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modification24 bp deletion in hTERT promoter	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineShanghai institute for biological scinces	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100MOI	In-vitro result30% cell killing after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID18281783
IDOV_2081	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration0.1 MOI	In-vitro resultNo cell death observed	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of senescence	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2082	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration1 MOI	In-vitro resultSome cell death observed	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of senescence	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2083	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration10 MOI	In-vitro resultSome cell death observed	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of senescence	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2084	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayCrystal violet staining	In-vitro virus concentration100 MOI	In-vitro resultAll cells was dead	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2085	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro resultAbsorbance decrease to below 0.2 after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2086	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro resultAbsorbance decrease to below 0.2 after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2087	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro resultAbsorbance decrease to below 0.2 after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2088	Virus nameAdenovirus	Virus strainMutant	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineNA	Origin of cell lineHuman cellosaurus cell line	Cell lineBEL-7404	Concentration of cell lineNA	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration1 MOI	In-vitro resultAbsorbance decrease to below 0.2 after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis	Immunogenic effectNA	Clinical trialNA	PMID21794078
IDOV_2690	Virus nameAdenovirus	Virus strainAdCN205-IL12	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-12 gene	Source of cell lineShanghai cell collection	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssaySpectrophotometer	In-vitro virus concentration10 MOI	In-vitro result85% cell viability after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID23028626
IDOV_2691	Virus nameAdenovirus	Virus strainAdCN205-IL12	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-12 gene	Source of cell lineShanghai cell collection	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssaySpectrophotometer	In-vitro virus concentration10 MOI	In-vitro result80% cell viability after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID23028626
IDOV_2692	Virus nameAdenovirus	Virus strainAdCN205-IL12	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-12 gene	Source of cell lineShanghai cell collection	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssaySpectrophotometer	In-vitro virus concentration10 MOI	In-vitro result60% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID23028626
IDOV_2693	Virus nameAdenovirus	Virus strainAdCN205-IL12	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-12 gene	Source of cell lineShanghai cell collection	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssaySpectrophotometer	In-vitro virus concentration10 MOI	In-vitro result50% cell viability after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMID23028626
IDOV_2739	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result100% cell viability after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2740	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result90% cell viability after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2741	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result82% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2742	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result78% cell viability after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2743	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus strain in combination with miR-34-a	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result90% cell viability after 24 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2744	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus strain in combination with miR-34-a	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result80% cell viability after 48 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2745	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus strain in combination with miR-34-a	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result60% cell viability after 72 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172
IDOV_2746	Virus nameAdenovirus	Virus strainAdCN205	Virus genome typeDNA	Virus familyAdenoviridae	Virus genome modificationNone	Virus aloneNo	Virus in combination with drug/radiationVirus strain in combination with miR-34-a	Immune gene insertion in viral genomeVirus expressing IL-24 gene	Source of cell lineATCC	Origin of cell lineHuman hepatocellular carcinoma cell line	Cell lineBEL-7404	Concentration of cell line1.0E+4 cells per well	In-vitro toxicityNA	AssayMTT assay	In-vitro virus concentration5 MOI	In-vitro result40% cell viability after 96 hours	Model organismNo	In-vivo virus concentrationNo	In-vivo toxicityNA	In-vivo resultNo response	Mode of deliveryNA	Pathway inducedInduction of apoptosis, G1 arrest and sensescence	Immunogenic effectInhibition of oncogene and antiapototic gene	Clinical trialNA	PMID23292172