Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 4. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3138Herpes simplex virusHSV-HSV-GRDNAHerpesviridaeDeletion of gamma 34.5 gene and insertion of GR and mcherryYesNoNoNational cell bak of IranMurine breast cancer cell line4T1NANAPhotomicrography and flow cytometry1 MOI27.9% cancer cell killingNoNoNA No responseNANANANA30936930
OV_4282AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman breast carcinoma4T14000 cells per wellNAMTT assay10 pfu26.27 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5369Maraba virusMG1RNARhabdoviridaeNoneYesNoNoATCCMurine triple negative breast cancer cell line4T1NANACoomassie brilinat blue staining4 micromolar70% cell killing after 48 hoursNoNoNA No responseNAInduction of apoptosisNAIn clinical trial for various cancer cell line27503504
OV_5372Maraba virusMG1RNARhabdoviridaeNoneNoVirus in combination with 2 micromolar palcitaxel for 48 hoursNoATCCMurine triple negative breast cancer cell line4T1NANACoomassie brilinat blue staining4 micromolar10% cell viability after 48 hoursNoNoNA No responseNAInduction of apoptosisImpaired IFN beta production by combinationIn clinical trial for various cancer cell line27503504