Primary information |
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OV_ID | OV_3138 |
Virus Name | Herpes simplex virus |
Strain | HSV-HSV-GR |
Virus type | DNA |
Virus family | Herpesviridae |
Modification in virus genome | Deletion of gamma 34.5 gene and insertion of GR and mcherry |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | National cell bak of Iran |
Origin of cell line | Murine breast cancer cell line |
Cell line | 4T1 |
Concentration of cell line | 0 |
In-vitro toxicity | NA |
Assay | Photomicrography and flow cytometry |
In-vitro virus concentration | 1 MOI |
In-vitro result | 27.9% cancer cell killing |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | NA |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 30936930 |