Browse By Cell Line Result Page of OvirusTdb

The total number of records retrieved from this search are 8. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3163Semliki forest virusSFV-VA7RNATogaviridaeNoneYesNoNoATCCHuman prostate cancer cell line22Rv140000 cells per wellNACell proliferation kit 1 assay0.01 MOI100% cell deathNoNoNA No responseNANANANA28557974
OV_3164Semliki forest virusSFV-VA7RNATogaviridaeNoneYesNoNoATCCHuman prostate cancer cell line22Rv140000 cells per wellNACell proliferation kit 1 assay0.1 MOI100% cell deathNoNoNA No responseNANANANA28557974
OV_3165Semliki forest virusSFV-VA7RNATogaviridaeNoneYesNoNoATCCHuman prostate cancer cell line22Rv140000 cells per wellNACell proliferation kit 1 assay1 MOI100% cell deathNoNoNA No responseNANANANA28557974
OV_3166Semliki forest virusSFV-VA7RNATogaviridaeNoneYesNoNoATCCHuman prostate cancer cell line22Rv140000 cells per wellNACell proliferation kit 1 assay10 MOI100% cell deathNoNoNA No responseNANANANA28557974
OV_3738Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell line22RV1NANANANANABalb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)1.0E+7 pfuNA Regression in tumor volume to 0.4 cm after day 80IntratumoralNANANA29696636
OV_3739Vesicular stomatitis virusVSV-GPRNARhabdoviridaevirus expressing GP proteinYesNoNoATCCHuman prostate cancer cell line22RV1NANANANANABalb/c-rag and gamma negative xenograft for 22Rv1 (2.0E+6)1.0E+7 pfuNA Complete regression in tumor after day 80IntravenousNANANA29696636
OV_4288AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman prostate carcinoma22Rv14000 cells per wellNAMTT assay10 pfu39.1 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_5067Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCMycobacterium tubeculosis cell line22RV11.0E+3 cells per wellNACrystal violet staining10 MOI40% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762