Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 32. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_2447Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2448Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI100% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2449Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI90% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2450Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI60% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2451Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.01 MOI10% cell survival after day 9NoNoNA No responseNANANANA22258815
OV_2486Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI100% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2487Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI70% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2488Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI30% cell survival after day 5NoNoNA No responseNANANANA22258815
OV_2489Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer0.10 MOI20% cell survival after day 7NoNoNA No responseNANANANA22258815
OV_2522Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI90% cell survival after day 1NoNoNA No responseNANANANA22258815
OV_2523Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI20% cell survival after day 3NoNoNA No responseNANANANA22258815
OV_2524Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 5NoNoNA No responseNANANANA22258815
OV_2525Vaccinia virusGLV-1h151DNAPoxviridaeDeteltion of TK gene and addition of GFP geneYesNoNoATCCHuman thyroid cancer cell line8505c3.0E+4 cells per wellNALDH release and spectrophometer1 MOI100% cell death after day 7NoNoNA No responseNANANANA22258815
OV_3119Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit0.25 MOI18% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3120Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit1 MOI40% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3121Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit2.5 MOI60% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3122Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit5 MOI75% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3123Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit10 MOI85% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3124Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit0.25 MOI30% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3125Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit1 MOI40% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3126Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit2.5 MOI60% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3127Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit5 MOI65% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3128Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit10 MOI70% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3129Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit0.25 MOI20% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3130Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit1 MOI35% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3131Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit2.5 MOI40% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3132Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit5 MOI50% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3133Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit10 MOI60% cells are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3134Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationNoVirus in combination with PAI-1 (25 microgram/ml)NoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5M3.0E+3 cells per wellNAuPA activity assay kit10 MOI90% cell are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3135Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationNoVirus in combination with PAI-1 (25 microgram/ml)NoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit10 MOI70% cell are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3136Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationNoVirus in combination with PAI-1 (25 microgram/ml)NoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell line8305C3.0E+3 cells per wellNAuPA activity assay kit10 MOI60% cell are deadNoNoNA No responseNACaspase dependent induction of apoptosis in vivo and in vitroNANA30969451
OV_3137Sendai virusuPA2RNAParamyxoviridaeDeletion of M, F gen at cytoplasmic locationYesNoNoJapan collection of research bioresources cell bankHuman anaplastic thyroid carcinoma cell lineKHM-5MNANANANANABALB/c nude mice xenograft for KHM-5M cell line (2.5E+5)1.0E+6 CIU per doseNA Reduction in tumor weight and increase in survival time 41.6 +/- 15 daysIntratumoralCaspase dependent induction of apoptosis in vivo and in vitroNANA30969451