| Primary information |
|---|
| OV_ID | OV_3136 |
| Virus Name | Sendai virus |
| Strain | uPA2 |
| Virus type | RNA |
| Virus family | Paramyxoviridae |
| Modification in virus genome | Deletion of M, F gen at cytoplasmic location |
| Virus alone | No |
| Virus in combination iwth drug/radiation | Virus in combination with PAI-1 (25 microgram/ml) |
| Immune gene induction in virus genome | No |
| Source of cell line | Japan collection of research bioresources cell bank |
| Origin of cell line | Human anaplastic thyroid carcinoma cell line |
| Cell line | 8305C |
| Concentration of cell line | 3 |
| In-vitro toxicity | NA |
| Assay | uPA activity assay kit |
| In-vitro virus concentration | 10 MOI |
| In-vitro result | 60% cell are dead |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Caspase dependent induction of apoptosis in vivo and in vitro |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 30969451 |