Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 64. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_3926Newcastle disease virusNDVstrain 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU51% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3927Newcastle disease virusNDVstrain 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU52% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3928Newcastle disease virusNDVstrain 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU47% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3929Newcastle disease virusNDVstrain 769RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU51% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3930Newcastle disease virusNDVstrain 769RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU47% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3931Newcastle disease virusNDVstrain 769RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU46% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3932Newcastle disease virusNDVstrain 860RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU28% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3933Newcastle disease virusNDVstrain 860RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU20% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3934Newcastle disease virusNDVstrain 860RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU25% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3935Newcastle disease virusNDVstrain 777RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU19% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3936Newcastle disease virusNDVstrain 777RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU17% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3937Newcastle disease virusNDVstrain 777RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU17% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3938Newcastle disease virusNDVstrain 14RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU61% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3939Newcastle disease virusNDVstrain 14RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU61% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3940Newcastle disease virusNDVstrain 14RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU41% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3995Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU42% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3996Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU24% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_3997Newcastle disease virusNDVwild 264RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU22% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4007Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU70% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4008Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU65% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4009Newcastle disease virusNDVwild 320RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU60% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4019Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU30% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4020Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU25% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4021Newcastle disease virusNDVwild 321RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU24% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4031Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU25% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4032Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU20% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4033Newcastle disease virusNDVwild 373RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU22% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4043Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU30% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4044Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU22% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4045Newcastle disease virusNDVwild 770RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU20% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4055Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU58% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4056Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU50% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4057Newcastle disease virusNDVwild 852RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU60% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4067Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay2 HAU50% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4068Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay8 HAU50% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4069Newcastle disease virusNDVwild 776RNAParamyxoviridaeNoneYesNoNoInstitute of clinical and experimental lymphology, RussiaHuman epitheloid cervix carcinomaHeLa10000 cells per wellNAMTT assay16 HAU45% cell survival after 4th dayNoNoNA No responseNAVirus induces apoptosis, necrosis and autophagy in cancer cellsInduction of MARK signalling pathwayNA29621357
OV_4279AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman cervix carcinomaC33A4000 cells per wellNAMTT assay10 pfu14.8 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4304AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman cervix adenocarcinomaHeLa4000 cells per wellNAMTT assay10 pfu66 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4332AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman cervix squamous cell carcinomaSiHa4000 cells per wellNAMTT assay10 pfu99.6 % cell viability after 72 hoursNoNoNA No responseNAActivation of cAMP signalling leads to induced expression of antiviral factors, severe ER stress and cell apoptosisNANA26373347
OV_4426Vesicular stomatitis virusRdBRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linkerYesNoNoATCCHuman cervical cancer cell lineC33A1.2E+4 cells per wellNAMTT assay21:1 particle to pfu50% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4427Vesicular stomatitis virusRdBRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, no addition of linkerYesNoNoATCCHuman cervical cancer cell lineHeLa1.2E+4 cells per wellNAMTT assay21:1 particle to pfu60% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4434Vesicular stomatitis virusRdB-1L-VSVGRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linkerYesNoNoATCCHuman cervical cancer cell lineC33A1.2E+4 cells per wellNAMTT assay24:1 particle to pfu48% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4435Vesicular stomatitis virusRdB-1L-VSVGRNARhabdoviridaeVirus expressing VSVG epitope, with no dletion in HI-loop, addition of single linkerYesNoNoATCCHuman cervical cancer cell lineHeLa1.2E+4 cells per wellNAMTT assay24:1 particle to pfu20% cell survival after 4 daysNoNoNA No responseNANANANA26430798
OV_4885Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay0.1 MOI100% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4886Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay1 MOI98% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4887Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay10 MOI88% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4888Adenoviruswild typeDNAAdenoviridaeNoneYesNoNoATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay50 MOI88% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4889Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay0.1 MOI90% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4890Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay1 MOI50% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4891Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay10 MOI10% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4892Adenoviruswild typeDNAAdenoviridaeAddition of IL21 gene in virus genomeYesNoVirus expressing IL-21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay50 MOI100% cell killing aftwr 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4893Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay0.1 MOI80% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4894Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay1 MOI20% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4895Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay10 MOI10% cell viability after 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_4896Adenoviruswild typeDNAAdenoviridaeAddition of IL21 and CCL21gene in virus genomeYesNoVirus expressing IL-21 and CCL21 geneATCCHuman cervix epithelial adenocarcinoma cell lineHeLa1 million cells per wellNAMTT assay50 MOI100% cell killing aftwr 7 daysNoNoSlightly toxic to HeLa as measured by LDH assay No responseNANAActivate proloferation of B-cell and Naive T-cellNA27157859
OV_5066Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman cervical cancer cell lineHeLa1.0E+3 cells per wellNACrystal violet staining10 MOI50% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5422Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI64% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5423Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI40% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5424Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-3-19.0E+3 cells per wellNAMTT assay1 MOI17% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5425Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI70% cell viability after 24 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5426Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI60% cell viability after 48 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5427Vaccinia virusLIVP-GFPDNAPoxviridaeDeletion mutant for tk geneYesNoNoRussian academy of scienceHuman cervical carcinomaKB-8-59.0E+3 cells per wellNAMTT assay1 MOI35% cell viability after 72 hoursNoNoNA No responseNAReduction production of IL-6 indicating tumor inhibitionNANA27538520
OV_5621Newcastle disease virusNDV-MK107RNAParamyxoviridaeNoneYesNoNoNAHuman cervical carcinoma cell lineHeLa80% confluencyNAMTT assay4 pfu50% of cancer cell death occursNoNoNA No responseNAInduction of apoptosis by virus infectionInduction of IFN-Gamma productionNAUS7470426
OV_5841Newcastle disease virusNDV-PPMK107RNAParamyxoviridaeNoneYesNoNoNAHuman cervical carcinoma cell lineHeLa80% confluencyNANA4 pfu50% cancer cell deathNoNoNA No responseNANANANAUS8105578