NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: tylophoridicine F

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790HepatomaHep G2367±116 nM ---The inhibitory effects of compound against NF-kappaB, CRE-, and AP-1-mediated transcription wad shown. The results indicate that this compounds preferentially inhibits NF-kappaB-mediated transcription, as the IC50 values in terms of NF-kappaB inhibition are significantly lower17531481

 






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