NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Silymarin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BAXBCL2-associated X protein581preneoplastic epidermal keratinocytesJB6 C141----Silymarin-induced apoptosis in JB6 C141 cells primarily mediated through a p53-dependent pathway, and p53-independent pathway seems to have a minor role. p53-dependent pathway involves the proteins of Bcl-2 family.15713892

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.