NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Inuviscolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
TP53tumor protein p537157MelanomaSK-28----Rapid inhibitory phosphorylation of Cdc2 (Thr14 and Tyr15) was seen early after treatment, followed by a later decrease in the expression level of both Cyclin b1 and Cdc2. Induction of p53 and p21wafi proteins and phosphorylation of p53 at Ser15 were also detected early after treatment.17919456

 






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