NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Home
Browse
Search
Advance Search
Data Submission

Compound: Evodiamine

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cell division cycle 25 homolog C (S. pombe)

Breast Carcinoma

NCI/ADR-RES

-

-

-

0.59±0.11 µM

Although the cyclin B1 expression was not upregulated during evodiamine treatment, Phosphatase cdc25c was observed to be hyperphosphorylated. This observation is consistent with the proposal that mitotic arrest in evodiamine-treated cells results from an increased cyclin B1/cdc2 kinase activity.

Help

FAQs

Statistics

Tool

Contact

Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.