NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: eurycomanone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
TP53tumor protein p537157HepatomaHep G2----Eurycomanone was cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53.19508737
TP53tumor protein p537157Lung adenocarcinomaA549----The expression of p53, a tumor suppressor protein that regulate the cell cycle and cell proliferation commonly overexpressed in cancer cells was also found reduced in the eurycomanone-treated cells when compared to the DMSO-treated control21903368

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.