NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: diosgenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP9caspase 9, apoptosis-related cysteine peptidase842Epidermoid carcinoma of larynxHep-2----At 24 h,caspase activities were enhanced significantly (1.2-fold for caspase-9 versus controls, p<0.01)15225412
CASP9caspase 9, apoptosis-related cysteine peptidase842TumorsM-4-BEU----caspase-9 activity was moderately induced at 12 and 24 h [1.3-(p<0.01) and 1.2-fold (p<0.05) at 12 and 24 h respectively versus controls] 15225412

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.