NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: diosgenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Epidermoid carcinoma of larynxHep-2----At 24 h,caspase activities were enhanced significantly (1.6-fold for caspase-3 versus controls, p<0.01)15225412
CASP3caspase 3, apoptosis-related cysteine peptidase836TumorsM-4-BEU----caspase-3 activity was more markedly induced at the same time (3.4- and 2.2-fold respectively versus controls, p<0.01)15225412

 






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