NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Chrysoeriol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
AKT1v-akt murine thymoma viral oncogene homolog 1207Multiple MyelomaKM335 µMol/L (48h)---The level of p-AKT (s473) in KM3 cells was repressed by 48 h incubation of IC50 chrysoeriol.21181363
AKT1v-akt murine thymoma viral oncogene homolog 1207Multiple MyelomaRPMI-822635 µMol/L (48h)---The level of p-AKT (s473) in RPMI 8226 cells was repressed by 48 h incubation of IC50 chrysoeriol.21181363
CCNB1cyclin B1891Multiple MyelomaKM335 µMol/L (48h)---Cyclin B1 was increased in the presence of chrysoeriol in KM3 cells.21181363
CCNB1cyclin B1891Multiple MyelomaRPMI-822635 µMol/L (48h)---Cyclin B1 was increased in the presence of chrysoeriol in these cells.21181363
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Multiple MyelomaRPMI-822635 µMol/L (48h)---An increasing tendency of p21 was observed in RPMI 8226 cells, but not in KM3 cells.21181363

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.