NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Chlorogenic acid

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790Murine epidermalJB6----Pretreatment of cells with chlorogenic acid markedly inhibited TPA-induced AP-1 and NF-kappaB activity over a similar concentration range . At a concentration of 40 µM chlorogenic acid, TPA-induced NF-kappaB activation was suppressed by 42%.15944151

 






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